The file contains the validation data on certified reference material for Nd isotope measurement, the LA-MC-ICP-MS composite Pb isotope ratios and Nd isotope time series for Tropic Seamount, north-east Atlantic Ocean. The dataset spans a deposition history covering the last 75 Ma. The record was obtained by analysis of hydrogenetic ferromanganese crust samples recovered during the 2016 JC142 expedition of the MarineE-Tech project.