Concentrations of SARS-CoV-2 RNA and physichochemical data on wastewater samples collected from six sites across England and Wales between March and July 2020. Also included are the number of COVID-19 positive tests and COVID-19 related deaths for the same period collated from publicly available records. COVID-19 data relate to the lower tier local authority that the wastewater treatment plant was located within. Full details about this dataset can be found at https://doi.org/10.5285/ce40e62a-21ae-45b9-ba5b-031639a504f7
