This dataset is a model output, from the Grid-to-Grid hydrological model driven by observed climate data (CEH-GEAR rainfall and Oudin temperature-based potential evaporation). It provides daily mean river flow (m3/s) for 260 catchments, for the period 1891 to 2015. The catchments correspond to locations of NRFA gauging stations (http://nrfa.ceh.ac.uk/). The data were produced as part of MaRIUS (Managing the Risks, Impacts and Uncertainties of drought and water Scarcity), which was a UK NERC-funded research project (2014-2017) that developed a risk-based approach to drought and water scarcity (http://www.mariusdroughtproject.org/). Full details about this dataset can be found at https://doi.org/10.5285/0ceb4f85-0bbf-49f0-ab70-cfc137ab7d4d