Cretaceous-Paleocene calcareous nannofossils from Site U1579 drilled on the Agulhas Plateau, Southwest Indian Ocean during International Ocean Discovery Program Expedition 392 Agulhas Plateau Cretaceous Climate in February-April 2022. The submitted files include data on Cretaceous-Paleogene (K-Pg) boundary calcareous nannofossil biostratigraphy and range chart, percentage assemblage counts and bulk carbon and oxygen isotopes from K-Pg sediment samples.